General Cell Based Assays
Eurofins Discoverx PathHunter eXpress DRD4 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0690E2CP0M)
The PathHunter DRD4 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD4 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD4 and EA-tagged β-Arrestin-2. Activation of DRD4 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter Human Complement C3a (C3AR1) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human Complement C3a (C3AR1) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure C3AR1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter CNR1 Bioassay Kit, 2-Plate. (93-0959Y2-00119)
The PathHunter CNR1 Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses ligand (e.g. CP 55,940) based activation of CNR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CNR1 and EA-tagged β-Arrestin-2. Activation of CNR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
Eurofins Discoverx PathHunter Human NMBR β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human NMBR β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure NMBR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human SSTR5 β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human SSTR5 β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure SSTR5 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF Human STING Binding Kit, 100,000 Assay Points
HTRF Human STING Binding Kit, 100,000 Assay Points
American Research Products Inc Mouse SuperoXide dismutase Mn
Mouse SuperoXide dismutase [Mn] mitochondrial (SOD2) ELISA kit from CUSABIO Detection Range 0 625 ng/mL-40 ng/mL Sensitivity 0 156 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Eurofins Discoverx PathHunter Human TrkA-P75 Functional Kinase Cell-Based Assay Kit (U2OS)
The PathHunter Human TrkA-P75 Stable Cell Line Functional Kinase Assay (U2OS) measures TrkA-P75 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human TBXA2R β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Human TBXA2R β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure TBXA2R (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress PTHR2 Total GPCR Internalization Assay, 2pl Kit. (93-0763E3CP0M)
The PathHunter PTHR2 Total GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of PTHR2 via detection of localization to the early endosome. The included cell line overexpresses ProLink-tagged PTHR2 and an EA-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the PTHR2 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress HRH3 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0103E2CP2L)
The cAMP Hunter HRH3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH3 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type HRH3, a naturally Gi/Go coupled GPCR. Upon activation of HRH3, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Indigo Biosciences INDIGO BIOSCIENCES INC Human TrkB Reporter Assay Kit, Cell-based, Luciferase, 384-Well
This all-inclusive cell-based luciferase reporter assay kit targets the Human Tropomyosin receptor kinases B (TrkB), also known as Neurotrophic Tyrosine Kinase Receptor, type 2 (NTRK2). It utilizes proprietary mammalian cells engineered to constitutively express TrkB, along with optimized media, a reference activator, Luciferase Detection Reagent, and a cell culture-ready assay plate. Its primary application is to screen test samples for functional activity, either activating or inhibitory, against human TrkB or the coupled Ca+2·calcineurin / NFAT signal transduction pathway.
- Clear, reproducible results
- All-inclusive assay systems
- Exceptional cell viability post-thaw
- Consistent results lot to lot
Meso Scale Discovery R-PLEX Mouse G-CSF ASY
The R-PLEX Mouse G-CSF Assay is a multiplex immunoassay panel that measures G-CSF in mouse samples such as serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and is designed for use on Meso Scale Discovery (MSD) instrumentation platforms The assay allows sensitive accurate and rapid quantification of G-CSF levels It requires a small sample volume and provides a dynamic range of up to 3 logs The panel is provided in a convenient all-in-one kit containing plates coated with capture antibodies detection antibodies calibrators and controls The assay takes approximately 3 5 hours to complete
Eurofins Discoverx PathHunter Human MLNR Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human MLNR Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure MLNR (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.