General Cell Based Assays
Eurofins Discoverx PathHunter eXpress AVPR1B Activated GPCR Internalization Assay, 10pl Kit. (93-0722E3CP5L)
The PathHunter AVPR1B Activated GPCR internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of AVPR1B via detection of localization to the early endosome. The included cell line overexpresses EA-tagged β-Arrestin-2 as well as a ProLink-tagged early endosome protein and untagged AVPR1B. Upon ligand-induced receptor activation, β-Arrestin-2 is recruited to the activated GPCR and the resulting AVPR1B-arrestin complex is internalized to the early endosome, leading to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mRXFP3 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0928E2MCP2L)
The PathHunter mRXFP3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. relaxin-3) based activation of mRXFP3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mRXFP3 and EA-tagged β-Arrestin-2. Activation of mRXFP3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HTR2C (VGV) U2OS β-Arrestin GPCR Assay, 10pl Kit. (93-0932E3CP19L)
The PathHunter HTR2C(VGV) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. serotonin) based activation of HTR2C(VGV) GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C(VGV) and EA-tagged β-Arrestin-2. Activation of HTR2C(VGV) stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress HRH1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0503E2CP2M)
The PathHunter HRH1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. histamine) based activation of HRH1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HRH1 and EA-tagged β-Arrestin-2. Activation of HRH1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery RPLEX HUM Neurotrophin3 ASY
The R-PLEX Human Neurotrophin-3 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures human neurotrophin-3 (NT-3) protein levels across samples This assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity up to 5 logs of dynamic range and low sample volume requirements The kit includes a 96-well plate pre-coated with capture antibodies specific for NT-3 detection antibodies calibrators and reagents required to perform the assay Quantitative results can be obtained in as little as 3 5 hours This assay is for research use only
Abcam Citrulline Assay Kit (Fluorometric)
Citrulline Assay Kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Creative Biomart Fructose Assay Kit is a quantitative colorimetric fructose determination at 565 nm.
Direct Assays: fructose in biological samples (e.g. serum, plasma, urine, saliva, milk, culture medium), food, juice, beverage and other agricultural products.Drug Discovery/Pharmacology: effects of drugs on fructose metabolism.Storage : Store all components at -20°C. Shelf life of six months after receipt.
Revvity Health Sciences Inc HTRF Human Phospho-STAT6 (Tyr641) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-STAT6 (Tyr641) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF CD32b (FcgRIIb) Cellular Binding Kit, 100 Tests
HTRF CD32b (FcgRIIb) Cellular Binding Kit, 100 Tests
Revvity Health Sciences Inc HTRF Human Total SYK Detection Kit, 500 Assay Points
HTRF Human Total SYK Detection Kit, 500 Assay Points
Medchemexpress LLC cGAS Human His-SUM 50ug
Recombinant human cyclic GMP-AMP synthase (cGAS) fragment (G161-F522) expressed in E. coli and supplied lyophilized with N-terminal 6xHis and SUMO tags to aid purification and solubility. Supplied amount for this item is 50 μg; other pack sizes are available. Activity testing is in progress and not guaranteed. Store lyophilized material frozen and aliquot after reconstitution per manufacturer's guidance.
- Recombinant fragment spanning residues G161-F522.
- N-terminal 6xHis and SUMO tags for purification and solubility.
- Expressed in E. coli for bacterial expression.
- Lyophilized formulation with trehalose for improved stability.
- Available in multiple pack sizes, including 50 μg.
- Activity testing in progress; no guaranteed activity.
- Recommend aliquoting and storage at -20°C or -80°C for long-term preservation.
Revvity Health Sciences Inc LANCE Ultra Phospho-eIF2α (Ser51) Detection Kit, 500 Assay Points
LANCE Ultra Phospho-eIF2α (Ser51) Detection Kit, 500 Assay Points